Hank Skinner was convicted of bludgeoning his girlfriend to death and fatally stabbing two of her children. Barring a reprieve, his execution has been set for November 9.
Skinner, 49, has not denied being present in the home at the time of the killings but he has insisted that DNA collected at the site could clear him as a suspect in the 1993 crimes.
Attorney Robert Owen told AFP his client was “deeply disappointed” at the US District Court’s ruling but “hopeful” it would be overturned. He plans to ask an appeals court to reconsider the request.
Texas has refused to carry out the tests on evidence found at the home ever since a jury convicted him in 1995.
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